Ancillary Studies Description

List of approved Ancillary studies to date:

1. Human papillomavirus (HPV) perinatal transmission and risk of HPV persistence among children: a pilot cohort study.
   Principal Investigator : Helen Trottier, Université de Montréal
   Co Investigators : François Coutlée, Marie-Hélène Mayrand, William D. Fraser, Patricia Monnier
2. Association between Maternal Obstructive Sleep Apnea-Hypopnea and Small for Gestational Age Infants.
   Principal Investigator : John Kimoff, Université McGill
   Co Investigators : Isabelle Marc, Frédéric Series
3. Estimating the risk of toxoplasmosis and cytomegalovirus infection in pregnant women.
   Co Principal Investigators : Valérie Lamarre, Université de Montréal ; Nicolas Gilbert, Santé Canada
   Co Investigators : Theresa Gyorkos, William D. Fraser
4. Assessment of physical activity and physical inactivity in children in the 3D cohort at 2 years of age.
   Co-Principal Investigators :  Isabelle Marc and Michèle Bisson, Université Laval
5. Elucidating the involvement of the Nodal signaling pathway in the pathogenesis of placental dysfunction leading to preterm birth or preeclampsia.
   Principal Investigator : Daniel Dufort, Université McGill
   Co Investigator : Patricia Monnier
6. Maternal mental health in pregnancy and early child emotional development: Psychosocial and biological mechanisms.
   Principal Investigator : Catherine Herba, Université du Québec à Montréal
   Co Investigators : William Fraser, Sarah Lippé, Sonia Lupien, Gina Muckle, Jean Séguin, Cathy Vaillancourt, Natalie Castellanos, Vivette Glover, Marie-Noëlle Simard, Gabriel Shapiro, Nathalie Houlfort, Clemens Kirschbaum
7. Challenges to the vulnerable child in the transitions from preschool to grade school in a pregnancy cohort (Transition Study).
   Principal Investigators : Jean Seguin, Université de Montréal et Sophie Parent, Université de Montréal
   Co Investigators : Gina Muckle, Sonia Lupien, William D Fraser, Michel Boivin
8. Using a randomized control trial to test developmental models of individual factors by environment interaction in the prediction of externalizing psychopathology across early school years.
   Principal Investigator : Natalie Castellanos-Ryan, Université de Montréal
   Co Investigators : Jean Séguin, William Fraser, Sophie Parent, Leila Ben Amor, Benoit Masse
9. The paternal contribution to neuroendocrine and neurodevelopmental trajectories of the offspring.
   Principal Investigator : Tuong-Vi Nguyen, Université McGill
   Co Investigators : Marie Brossard-Racine, Patricia Monnier, Anna Naumova, Jacquetta Trasler, Sophie Parent, Simon Ducharme, Jean Seguin
10. MicroRNAs in pregnancy and gestational diabetes: origin and functions for clinical applications.
    Principal Investigator : Luigi Bouchard, Université de Sherbrooke
    Co Investigators : Renée Guérin, Patrice Perron, Marie-France Hivet, Michelle Scott
11. Talking at home and at school: The developmental trajectory of oral language among young children who speak minority languages.
    Principal Investigator : Andrea MacLeod, University of Alberta
    Co Investigators : Jean Séguin, Sophie Parent, Natalie Castellanos Ryan
12. Intrauterine Inflammation as a Determinant of Pregnancy Outcome and Child Health
    Principal Investigator: Alan Rosenberg, University of Saskatchewan
    Co-investigators: Darryl Adamko, Mara Erlandson, John Gordon, Munier Nour, Mark Inman,  et al.
13. Placental epigenetic variations associated with adiposity in early-childhood: A replication study in the 3D Cohort. Principal Investigator: Luigi Bouchard, Université de Sherbrooke. Co-Investigators: Valérie Gagné-Ouellet, Marie-France Hivert, Patrice Perron
14. Maternal sleep-disordered breathing during pregnancy and long-term health outcomes in children: the 3D pregnancy and birth cohort. Principal Investigator: S.Pamidi, McGill University. Co-Investigators: E. Constantin, N. Huynh, J. Séguin, I. Marc, W. Fraser, A. Benedetti, F. Sériès , R.J. Kimoff
15. Cytomegalovirus non-primary infection during pregnancy in Quebec: prevalence, risk factors, consequences on pregnancy and the newborn. Principal Investigator: Isabelle Boucoiran, Université de Montréal. Co-Investigators: Safari Joseph Balegamire, Christian Renaud, Valérie Lamarre, Benoît Mâsse, Yves Giguère
16. Safety and effectiveness of influenza vaccine during pregnancy. Principal Investigator: Anick Bérard, Université de Montréal. Co-Investigators: Sasha Bernatsky, Mark Walker, William Fraser
17. Prenatal Alcohol Exposure (PAE) Harmonization using Maelstrom ReACH Catalogue. Principal Investigator: Alan Bocking, University of Toronto. Co-investigators: Isabel Fortier, Sonia Anand, Nicole Letourneau.
18. Effects of taking antidepressants during pregnancy on the psychomotor, mental and language development of the child at 2 years’ age. Principal Investigator: Gina Muckle, Université Laval. Co-investigator: Noémie Tanguay
19. The two-way relationship between maternal depression and the emotional mother-child relationship: the moderating role of breastfeeding. Principal Investigator: Natalie Castellanos-Ryan, Université de Montréal. Co-investigator: Elizabeth Morin
20. Impact of prenatal exposure to stress on preterm birth and development of toddlers: A ReACH/EUCAN Connect study using data from several birth cohorts. Principal Investigator: Isabel Fortier,  Université McGill. Co-Investigators: Julie Bergeron,  Anne-Marie Nybo Andersen.
21. Maternal psychological characteristics and weight gain during gestation. Principal Investigator: William Fraser, Université de Sherbrooke. Co-investigators: Jean Patrice Baillargeon, Isabelle Hardy
22. Urban exposome in early-life and motor and cognitive function in children. Principal Investigator: Monica Guxens, Barcelona Institute for Global Health. Co-Investigators: Anne Claire Binter, Martine Shareck, William Fraser